Difference between revisions of "Industrial fermentation"

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=== Dairy waste ===
=== Dairy waste ===
Whey, the liquid by-product of cheese manufacturing, typically contains 4% lactose, 1%
Whey, the liquid by-product of cheese manufacturing, is used as a source of fermentable carbohydrate and nitrogen.
 
protein, 1% ash, and some lactic acid as shown in table 12. Whey is used as a source of
 
fermentable carbohydrate and nitrogen.


=== Pre-treatment ===
=== Pre-treatment ===
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=== Microorganisms ===
=== Microorganisms ===
In practice, well-known, productive and harmless production organisms are used that, equipped with the new genetic information, will produce the desired products in high yield and efficiency. These are the so-called GRAS organisms (Generally Regarded As Safe) and belong to the genera ''Bacillus, Aspergillus, Penicillium, Saccharomyces'', etc. A major advantage is that these genetically modified microorganisms do their work under controlled conditions in a fermenter or bio-reactor, carefully contained and separated from the outside world (contained environment). They cannot escape from the factory so that ecological problems or concerns regarding the release of genetically modified organisms in the environment are avoided.
Microorganisms used in industrial fermentations include: bacteria, yeast and mold. In practice, these are well-known, productive and harmless (GRAS - Generally Regarded As Safe) production organisms, equipped with the new genetic information, that are used to produce the desired products in high yield and efficiency. A major advantage is that these often genetically modified microorganisms do their work under controlled conditions in a fermenter or bio-reactor, carefully contained and separated from the outside world (contained environment). They cannot escape from the factory so that ecological problems or concerns regarding the release of genetically modified organisms in the environment are avoided.


=== Equipment ===
=== Equipment ===
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* a cleaning and sterilization system: to avoid contamination with other, undesired microorganisms
* a cleaning and sterilization system: to avoid contamination with other, undesired microorganisms


Industrial production fermenters are mostly made of stainless steel, while labfermenters are made from glass.
=== Operating conditions ===
As it involves living organisms, a fermentation process is typically conducted under mild conditions (pH and temperature). As a result, the energy consumption is relatively low as well as the capital and operating costs. However, fermentation technoloiges are complex and sensitive requiring careful control of quality and safety of the raw materials, process parameters, contamination, etc.  


=== Operating mode ===
Industrial fermentations may be carried out as batch, fed-batch, or  continuous culture systems. Batch and fed-batch operations are quite common, continuous fermentations being relatively rare <ref>{{Cite book|author=Y. Chisti|year=2014|book_title=Encyclopedia of Food Microbiology (Second Edition)|publisher=Science Direct}}</ref>.  
Industrial fermentations may be carried out as batch, fed-batch, or  continuous culture systems. Batch and fed-batch operations are quite common, continuous fermentations being relatively rare <ref>{{Cite book|author=Y. Chisti|year=2014|book_title=Encyclopedia of Food Microbiology (Second Edition)|publisher=Science Direct}}</ref>.  


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=== Biomass ===
=== Biomass ===
Single cell protein (SCP) can be used as food or feed.
 
* Single Cell Protein
* Baker's yeast
* Lactic acid bacteria


=== Bio-products ===
=== Bio-products ===


==== Enzymes ====
==== Enzymes ====
* Proteases
* Lipases
* Amylases
* Cellulases
* Peroxidases


==== Biopolymers ====
==== Biopolymers ====
* Polyhydroxyalkanoates (PHA)
* Polysaccharides: xanthan gum, dextran
'''Flavors'''
* Monosodium glutamate (MSG)


==== Biocolorants ====
==== Biocolorants ====
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==== Organic acids ====
==== Organic acids ====


* '''Lactic acid''' had widespread applications in a range of industries: cleaning agents, personal care, food preservative, medical use, etc. It is also the precursor for polylactic acid (PLA), a biodegradable plastic.
* Acetic acid
*Lactic acid  


* '''Citric acid''' a food additive
* Citric acid  
*Tartaric acid
*Fumaric acid


==== Alcohols ====
==== Alcohols ====


* Ethanol
* Ethanol
*Butanol
*Glycerol
*Butanediol


==== Vitamins ====
==== Solvents ====
 
* Vitamin C
 
* Vitamin-B12


==== Antibiotics ====
* Acetone


==== Pharmaceuticals ====


* Vitamins: vitamin C, B12
*Antibiotics: penecilin
*Hormones


Amino-acids
==== Pesticides ====


'''Biosurfactants'''


'''Oils'''


Several products possible, examples
* Single cell oil


* Speciality carbohydrates,
==== Amino-acids ====
* Industrial enzymes
* surfactants
* organic acids
* solvents
* flavours and fragrances
* biostimulants
* polymers
* protein concentrates
* nutraceuticals
* advanced fuels


== Post-treatment ==
== Post-treatment ==
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