Difference between revisions of "Field-Flow fractionation (FFF)"

Different variants of the FFF are available, which includes Asymmetric flow FFF (AF4), centrifugal FFF, electrical FFF (EFFF), split flow thin-cell fractionation (SPLITT), and thermal FFF (TF3). Depending on the applied technology particles can be separated in dependence of different physicochemical properties.

In Thermal FFF the separation force is established by applying a temperature gradient. the top wall of a Thermal FFF channel is heated up, while the bottom wall of the channel is cooled down. The higher the temperature difference between both plates of the separation channel, the higher is the separation force. In order to achieve optimum separation, the temperature difference across the elution time can be adjusted. TF3 is well suited to the separation of polymers and organic solvents.