Difference between revisions of "Chromatography"

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===ABC===
=== Bio Base Europe Pilot Plant ===
{{Infobox provider-chromatography}}
{{Infobox provider-chromatography|Company=Bio Base Europe Pilot Plant|Country=Belgium|Webpage=https://www.bbeu.org/what-we-offer/technologies/product-recovery-and-purification/|Technology name=Chromatography|TRL=4-6|Other=Preparative chromatography unit (GRACE) – BENCH scale, adsorption chromatography for ATEX environment,|Capacity=-ion exchange in water treatment columns: lab scale up to 3000 L columns (and everything in between)
describe the company, here is an example
-Exclusion chromatography, bind & elute chromatography… in packed bed columns: 250 mL, 8 L, 10 L, 38 L, 60 L columns|Pressure=5|Temperature=50 °C|Processable volume=8l;38l; 80l; 900l|Contact=chromatography@bbeu.org|Image=Logo Bio Base Europe Pilot Plant.png|Mobile phase=Process dependent! Mostly it is watery products but we can use solvents as well.|STationary phase=Resins = Process dependent!|Feedstock=chemical compounds of biological origin|Product=separated hydrocarbons}}
Bio Base provides scale up of chromatography processes from lab-scale up to 4000 L scale. There is mainly a very broad knowledge of anion exchange, cation exchange and activated carbon processes, since (economically) those are most realistic to scale-up.
 
===Veg'Extra===
{{Infobox provider-chromatography|Company=Veg'Extra|Country=France|Webpage=https://en.vegextra.com/|Technology name=|Mobile phase=|STationary phase=|Temperature=|Pressure=|Feedstock=Any liquid biowaste|Product=Separated fractions|Processable volume=200 - 800}}
 
Veg’Extra has 25 years of experience with currently 300 tons of production per year. As a service provider, it supports you in your projects, advises you and sets up an industrial process for the production of your extracts (actives and ingredients). 25 employees have a wide range of expertise in extraction, separation, purification. Wide range of solvents can be used, except when it is classified as carcinogenic, mutagenic, reprotoxic (CMR).
 
===XPure Systems===
{{Infobox provider-chromatography|Company=XPure Systems|Country=The Netherlands|Webpage=https://xpure-systems.com/|Technology name=XPure-C, XPure-S, XPure-E, XPure-R|Mobile phase=|STationary phase=|Temperature=|Pressure=Up to 30|Feedstock=Any liquid biowaste|Product=Separated fractions|Processable volume=100 - 5000|Capacity=0.1 - 200|TRL=5 - 7}}
 
XPure is committed to improving separation efficiency by designing and delivering innovative, customized continuous ion exchange and chromatography systems. XPure uniquely features expanded bed adsorption technology that is integrated in our SMB configured systems. This enables us to directly process particulates containing feed streams, for example from fermentation or plant based juice streams.
 
XPure’s Simulated Moving Bed (SMB) technology overcomes the intermittent nature of classical chromatography by introducing more columns, thus allowing for simultaneous separation to occur. XPure’s patented technology for continuous chromatography and ion exchange enables the isolation of desired components from such complex mixtures while improving yield and purity at lower costs. Our systems integrate modular and scalable simulated moving bed hardware with a smart and flexible software platform, enabling the flexibility to implement a wide range of process control strategies. This holistic approach reduces resin and solvent consumption and increases product concentrations, purity, and yields. This singular focus on process technology and equipment means we are independent of resin and media suppliers. Rather, our team of experts deliver the suitable and cost-effective solutions to meet your separation requirements.
 
XPure enables the purification of bio-based chemicals and mild fractionation of food components using an efficient technology that contributes to a sustainable process industry.


''ABC was founded in 20... 12 by KNN and Syncom, in collaboration with the university of Groningen, Netherlands. The company is a technology provider developing chemical recycling technologies for different feedstocks including non-food bio- and plastics waste. In 2018 a pilot plant with the capability to process biomass and plastic waste was set up at the Zernike Advanced Processing (ZAP) Facility. The company is now focused on setting up their first commercial plant with a capacity of 20,000 to 30,000 tonnes. The investing phase B was recently completed, with the last investment phase in 2019 the financial requirements are fulfilled to complete the commercialisation activities to build the plant which is expected for 2023.''
===W.R. Grace & Co.===
{{Infobox provider-chromatography|Company=W.R. Grace & Co.|Country=Germany, Spain, Sweden|Webpage=https://grace.com/|Technology name=TRISYL (R) silicas|Mobile phase=Oil|STationary phase=99.7% SiO2|Temperature=70 - 90|Pressure=1|Feedstock=Any liquid biowaste|Product=Biobased diesel and HVO}}


describe their technology, here is an example
Grace Catalysts Technologies and Grace Materials Technologies provide innovative products, technologies and services that improve the products and processes of our customers around the world. Grace was founded as W.R. Grace & Co. in 1854 in Peru and currently has locations in Germany, Spain, and Sweden. Our assets and expertise enable us to collaborate with our customers from the R&D laboratory, through multiple pilot plants, on up through commercial production.  Technology Centers are integrated with manufacturing so that commercialization of new products is accelerated.  Award-winning Technical Service teams work seamlessly alongside customers to find ways to increase value in our customer processes as well as their products.


''The technology is based on an Integrated Cascading Catalytic Pyrolysis (ICCP) process, being able to produce aromatics including benzene, toluene, and xylene (BTX) as well as light olefins from low grade biomass and plastics waste. This technology utilises catalytic cracking in a two-step process at temperatures between 450- 850 °C. In the first step the feedstock material is vaporised via thermal cracking. The pyrolysis vapours are then directly passed into a second reactor in which they are converted into aromatics by utilising a zeolite catalyst which can be continuously regenerated. Finally, the products are separated from the gas via condensation. An ex situ approach of catalytic conversion has several advantages such as the protection of the catalyst from deactivation/degradation expanding its lifetime, a greater variety of feedstock, and a precise adjustment of process conditions (e.g. temperature, catalyst design, and Weight Hourly Space Velocity (WHSV) in each step for improved yields. In current pilot plant with 10 kg h-1 feed capacity for either waste plastics or biomass, final design details are established, which will be include in the running engineering activities for the commercial plant.''
From pre-treatment of the vegetable oils and fats to the final polishing or post-treatment, Grace’s TRISYL<sup>®</sup> silica is proven technology that results in more process savings compared to clay or silicates. Our silica technology comprised of highly pure synthetic amorphous silica was developed for maximum adsorption and significantly reduces phospholipids, trace metals and animal proteins in both physical and chemical refining operations. Recommended for the pre-treatment of feedstock for both renewable diesel and first generation biodiesel, TRISYL<sup>®</sup> silica can also be used in biodiesel post-treatment by helping to substantially reduce the need for water washing. TRISYL<sup>®</sup> silica enables the economic conversion of biomass to biodiesel and renewable diesel to be more efficient and environmentally sustainable.


=== Bio Base Europe Pilot Plant ===
Renewable diesel – commonly referred to as green diesel or HVO (hydrotreated vegetable oil) – continues to grow in prevalence. Grace’s TRISYL<sup>®</sup> silica helps maximize service life of catalysts by consistently removing trace materials and impurities from difficult-to-refine feedback and helps achieve economies of scale in renewable diesel production. Unlike activated bleaching earth (ABE), TRISYL<sup>®</sup> silicas provide superior adsorption capacity for phospholipids and metals at all free fatty acid concentrations. This reduces costs on spent solids and disposal but also reduces oil lost during pre-treatment.
{{Infobox provider-chromatography|Company=Bio Base Europe Pilot Plant|Country=Belgium|Webpage=https://www.bbeu.org/what-we-offer/technologies/product-recovery-and-purification/|Technology name=Chromatography|TRL=4-6|Other=Preparative chromatography unit (GRACE) – BENCH scale, adsorption chromatography for ATEX environment,|Capacity=-ion exchange in water treatment columns: lab scale up to 3000 L columns (and everything in between)
-Exclusion chromatography, bind & elute chromatography… in packed bed columns: 250 mL, 8 L, 10 L, 38 L, 60 L columns|Pressure=5|Temperature=50 °C|Processable volume=8l;38l; 80l; 900l|Contact=chromatography@bbeu.org|Image=Logo Bio Base Europe Pilot Plant.png|Mobile phase=Process dependent! Mostly it is watery products but we can use solvents as well.|STationary phase=Resins = Process dependent!|Feedstock=chemical compounds of biological origin|Product=separated hydrocarbons}}
Bio Base provides scale up of chromatography processes from lab-scale up to 4000 L scale. There is mainly a very broad knowledge of anion exchange, cation exchange and activated carbon processes, since (economically) those are most realistic to scale-up.


== Open access pilot and demo facility providers ==
== Open access pilot and demo facility providers ==
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